Sentence examples for mutants cause a from inspiring English sources

We therefore tested whether the shs1-ps mutants cause a phenotype that is similar to shs1Δ.

APC mutants cause a strong activation of canonical Wnt signaling that leads to arrest prior to gastrulation [36].

In conjunction, the data from the AJ and more basal sections suggest that the mutants cause a subcellular reshuffling of endogenous protein, possibly linked with its signalling ability.

In particular, we found that these histone mutants cause a shift in the distribution of Spt16 toward the 3′ regions of the transcribed genes we investigated.

In Drosophila wing or eye epithelia, mutation of ex is sufficient to cause mild tissue overgrowth, but ex, mer double mutants cause a much stronger overgrowth phenotype, similar to hpo or wts mutants (Hamaratoglu et al, 2006).

This revealed that mago, btz, and TmIIgs mutants cause a highly significant reversal in the directional bias, with 57%–59% of particles moving anteriorly, compared to only 43% in wild-type.

The JNK cascade can be inactivated by the MAPK phosphatase VHP-1, and vhp-1-null mutants cause an arrest in developmental growth at the early larval stage due to hyperactivation of the JNK pathway (Supplementary Fig. 1 17.

As previously shown for H3-L61W (Duina et al. 2007; Nguyen et al. 2013), the H3-L61X mutants cause an overall shift in Spt16 occupancy toward the 3′ ends of the PMA1 and FBA1 genes (see Figure 3, C and F).

Furthermore, overexpression of CMT2B-causing Rab7a mutants caused a strong increase of soluble vimentin (Fig. 4E F).

Reintroduction of a functional RRN5 gene into Sup mutants caused a reduction in the number of rDNA repeats to close to the wild type level but did not change RNA content.

Thus, reduced accumulation of Pio in the tracheal lumen in γCOP mutants causes a pio-like defect in dorsal branch formation.