Sentence examples for mutants cannot be from inspiring English sources

They are also similar in that they utilize the antigen receptor to transmit their signals to the cell since CD3-TCR mutants cannot be activated via either CD2 or the toxin receptor.

However, the failure of forebrain maintenance in these mutants cannot be attributed to the neural tube closure defect since Wnt1 Cre Dbx1DTA embryos, which also display an opened brain at E9.5 (data not shown), form a forebrain.

While menin is required for Hsp70 expression, the results of epistatic studies indicate that the increase in genome instability observed in Mnn1 lack-of-function mutants cannot be accounted for by mis-expression of Hsp70.

Moreover, the total protein level of NOS isoforms is unchanged, indicating that the increase in basal NOS activity seen by NO fluorescent imaging in the mutants cannot be explained by a change in isoform expression.

Preliminary data from our laboratory demonstrates that Ncad may genetically interact with other Rac GEFs to affect earlier CNS development Ncad mutants cannot be rescued by expression of RacWT alone in the CNS (Biersmith, B. and Geisbrecht, E.; unpublished data).

Externally, xav mutants cannot be distinguished from WT until after 48 hpf, when they start to exhibit a bent tail and slower heart beat, phenotypes that become progressively more severe (Figure 1A, 1B).

The better performance of the E53K variant suggests an improved antitoxin activity against Hha, although the possibility that TomB has some residual toxicity that is reduced in the E53K mutant cannot be ruled out.

If a mutant cannot be distinguished from the original, it is called equivalent.

Fig. 3F shows that the NPM/B23 S4A-mutant cannot be phosphorylated by active Plk2.

However, they also demonstrate that the biofilm-defect in a sarA mutant cannot be explained by its impact on either nuclease or proteases alone.

However, the lack of BOS1 activation with the pelBC mutant cannot be accounted for by differences in symptom severity since pelBC and pelDE mutants exhibited similar virulence on Arabidopsis (data not shown).