Your English writing platform
Discover LudwigSuggestions(3)
Exact(4)
The results show that the final size of infections may be reduced only if treatment is scaled down to the optimal level during the early stages of the pandemic (Figures 5a), before outbreaks of compensated mutants can occur (Figure 6a).
Therefore, the loss of anti-Bax function in PrP mutants can occur through two mechanisms: low levels of CyPrP through decreased retrotranslocation or pre-emptive quality control and loss in anti-Bax activity for those mutants that can generate CyPrP.
This suggests that GTP exchange in Rab7 mutants can occur in an unregulated, GEF-independent manner.
Simulations indicate that, within this zone, coexistence of solely vertically transmitted feminisers with horizontally transmitted mutants can occur.
Similar(55)
Mutation can occur in two directions; mutation from wild type to mutant is called a forward mutation, and mutation from mutant to wild type is called a back mutation or reversion.
Thus, these two phenotypical changes of OHCs of the Cdc42 mutant mice can occur independently of each other.
Deleterious, neutral, advantageous, and compensatory mutants can all occur within this spectrum, resulting in a population that is largely replication defective [8].
As with many tumour suppressor genes, inactivation of the remaining wild-type allele in MSH2 mutant tumours is common and can occur either by somatic mutation (Cunningham et al, 2001; Leach et al, 1993) or loss of heterozygosity (LOH) (Potocnik et al, 2001; Yuen et al, 2002).
Cryo-immuno EM confirms that in both Cln3 Δex1-6 and control RPE, phagolysosomes containing mixed cathepsin D and rhodopsin-positive POS are present, i.e. that lysosomal fusion and hydrolase delivery to phagosomes can occur in mutants, but we found almost doubled numbers of phagosomes compared with wild-type accumulated in the basal RPE region where lysosomal fusions take place.
Other observations indirectly suggest that loss of epigenetic methylation can occur in certain mutants with replication fork crowding, specifically dam, topA, rnhA, and recG for EcoKI; rnhA and recG for EcoR124I.
It has to be noted that although minor changes in the secondary structure can occur, all Ala mutants displayed similar predicted α-helical properties as the wild-type BH4-Bcl-2 using PSIPRED vs3.0 (Supplementary Figure 4, http://bioinf.cs.ucl.ac.uk/psipred/).ac.uk/psipred/
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com