Sentence examples for mutants at one from inspiring English sources
Owens and co-workers from Celltech (now part of Union Chimique Belge, UCB) prepared serine- or threonine-to-cysteine mutants at one of five sites on the CH1 domain of an antibody against the tumor-associated glycoprotein TAG72.
One 96-well plate allows for the determination of the Sav FBS concentration of one 24-well plate containing the twelve mutants at one amino acid position of Sav.
Unlike in the one-dimensional case, an outcropping of mutants at one latitude may be rivalled by an outcropping of wild types at another latitude.
For each of the 40 resistant mutants at least one putative resistance mechanism was identified, including mutations to previously described antimicrobial drug targets and promoters of drug targets, drug-modifying (activating) enzymes, regulators of efflux pumps, RNA polymerases and mutations to other metabolic and biochemical processes that may contribute to resistance (Table 3).
However, each mouse can only harbor two different copies of a mutant gene at one locus.
Liver tissues from wildtype and mutant mice at one year of age were collected for mRNA extraction and gene expression analyses.
Microinjection of ptena mRNA in ptena −/−ptenb −/− mutants at the one-cell stage suppressed the enhanced angiogenic phenotype at 4 dpf (Fig. 2D,D′).
If the intermediate one-point mutants (at least one of them) have larger fitness value than the two-point mutant would have in the absence of epistasis then the effect would be strong.
The high level of expression that occurs at 29°C results in pupal lethality (headless phenotype) in 99% flies that are homoplasmic for mitochondrial genomes mutant at only one site and the few survivors are eyeless or have a small eye phenotype.
In the EW crossing assay, one copy of the Robo2 FL cDNA BAC provides a significant rescue of robo2, fra double mutants at stage 16, whereas one copy of the Robo2ΔIg2 BAC has no effect.
To examine the potential for preventing cleavage at the 38/42 sites, we produced further Fwt heterodimer mutants designed to block cleavage at one or more of these sites, and at a third putative alternative 38/42 site unique to MSP1-F.
