Sentence examples for mutants as detected from inspiring English sources

However, steady state levels of these mutants, as detected by anti-HA Western blotting in the absence of cycloheximide, appeared to be similar to that of WT Hhat.

This milder phenotype correlates with our finding that Notch activity is still present in the V1 domain of Jag1 mutants, as detected by the expression of the Notch target and effector Hes5.

The IMS image of each PC species revealed similar PC composition differences between the wild-type and fat-1 mutants as were detected using LC-ESI-MS/MS (Fig.  5c).

Another early born retinal neuronal type, the horizontal cells, exhibited abnormally exuberant dendritic arbors in the Dnmt1 mutant as detected by neurofilament labeling.

That clone may have had additional mutations in the genome beyond the mutant P66, but we did verify that all genomic plasmids present in the parental strain were present in the mutant as detected by end point PCR on the day of inoculation into mice.

Our quantitative Western blot analyses demonstrate that WRN expressed in yeast at levels comparable to that previously reported in several human cell lines was sufficient to restore growth in the sgs1 top3 mutant as detected by plate streak studies or liquid culture growth analysis.

Mutant p53, as detected by sequence analysis, predicts treatment failure in patients with rectal cancer treated with radiotherapy or chemoradiation (RR 1.49; c.i. 1.25 1.77).

Germline transmission was determined by crossing male chimeric mice to FVB/n females and the offspring were scored for either coat color transmission or presence of the mutant allele as detected by PCR.

Duplication of the SPB is unlikely to be affected in these pcp1 mutants, as we detected two separate Sid4 mRFP signals (e.g., time point 12 min; Figure 1D).

Biochemical experiments indicated that Cdc42 was able to exchange between different lipid vesicles in vitro even in the absence of a GDI (Johnson et al., 2009), and there was still a substantial pool of Cdc42 in the cytoplasm of rdi1Δ mutants lacking a GDI, as detected either by fractionation (Tiedje et al., 2008) or fluorescence correlation spectroscopy (Das et al., 2012).

Active LIMK1/2 bound to both the wild-type and mutant fascin-1 proteins, as detected with an antibody to T508/T505-phosphorylated LIMK1/2.