Sentence examples for mutants are highly from inspiring English sources
All these mutants are highly UV and MMC sensitive, and lose cellular viability at 4°C, similar to recD mutants.
SDS-PAGE analysis showed that while V1F, V1D and V1L mutants are highly stable at high concentrations of SDS, the V1G is highly susceptible to denaturation.
In the current paper, we first analyze the behavioral properties and ultrastructure of adult muscles in rt and/or tw mutants and then provide evidence that these mutants are highly useful for elucidating the mechanism of muscular dystrophy.
Previous inability to solubilize insoluble protein without adding denaturants and detergents retarded our complete understanding of the mechanisms underlying protein folding and disease-relevant aggregation because many folding intermediates and disease-causing mutants are highly insoluble.
Both not4Δ and bur2Δ mutants are highly sensitive to hydroxyurea and hygromycin B, while the not4S/T5A yeast strain is weakly sensitive to hydroxyurea and mildly sensitive to hygromycin B (Figure 4A).
Arabidopsis NPR1 mutants are highly susceptible to biotrophic infections.
All obtained mutants were highly resistant to azoxystrobin and their resistance was genetically stable.
The more severe alterations in RAM morphology in the rpt5a mutants compared with rpn8a/heb3 mutants exposed to high-B were consistent with the finding that the rpt5a mutants were highly susceptible to high-B stress as indicated by root growth.
We found that root growth in the rpt5a mutants was highly sensitive to HDAC inhibitors, TSA and sodium butyrate (NaBT) (Fig. 10a), similarly to high-B stress (3 mM B) (Supplementary Fig. 5), indicating that histone hyperacetylation is a key process for evoking high-B hypersensitivity in the rpt5a mutants.
However, our studies showed that these mutagens were stable without any drastic changes in the cellulase production profiles and corresponding enzyme activities for several subsequent generations indicating that the developed mutants were highly stable.
Some of these mutants were highly susceptible to trypsin degradation Cry4Ba-A145CCry11Aa-N128D58A, Cry11Aa-Q135C and Cry11Aa-Q135C) and were not further analyzed.
