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The crown root less 1 (Inukai et al. [2005]) and adventitious less 1 (Liu et al. [2005]) mutants are both impaired in the OsLBD3-2 gene, which encodes a LATERAL ORGAN BOUNDARY DOMAIN (LBD) transcription factor belonging to a specific clade regrouping LBD proteins involved in the control of post-embryonic root initiation in different species (Coudert et al. [2013a]).
The pmt3-K14R and pmt3-K14R,K30R mutares are both sensitive to HU (5 mM), while pmt3-K30R is very slightly sensitive to HU.
The Δfsd-1 and Δvib-1 mutants are both defective in female sexual development.
Generally, genes down-regulated and up-regulated in rx3 -/- mutants are both enriched in the biological processes " Metabolism", " Regulation" and " Development".
We note that both RasG and RasS mutants are both partially defective in macropinocytosis and yet the Raf1-RBD reporter still localises to nascent macropinosomes in both strains.
These mutants are both unable to influence the nuclear retention of TLE proteins, although they are able to bind to TLE.
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The wild type and the mutants were both assayed for in vitro phosphodiesterase activity with bis p-nitrophenyl) phosphate as the subis p-nitrophenyl
The development and standardisation of sensitive, valid behavioural tests which are suited to phenotype mouse mutants is both a responsibility and a challenge to investigators of mouse behaviour.
The Newman tagO and cap5O mutants were both significantly attenuated for abscess induction when compared to the parental strain.
On the other hand, Stat1 and its phosphorylation mutants were both nuclear and cytoplasmic in the reconstituted Ras-transfected MEFs (Fig. 4A).
The prkaca-L173A and prkaca-F327A mutants were both selected for suppressor screening since they provide two unique backgrounds: L173A lies within the conserved kinase core while F327A lies within the non-conserved C-terminal tail.
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