Sentence examples for mutants and tested from inspiring English sources
We generated the complete set of single nucleotide point mutants and tested their transcription activity.
We also assembled minichromosomes in the presence of the H1.4 domain mutants and tested their affinity for chromatin and effect on nucleosome spacing.
In an effort to further map the respective epitopes bound by these rhAbs, we generated an additional series of rHA mutants and tested the ability of both rhAbs to bind to the expressed rHA products by IFA.
To explore the roles of the RPEL-repeat and PP1-binding domains, we made actin-binding and PP1-binding deficient mutants and tested their ability to stimulate cell spreading.
To test whether the glyoxylate shunt plays a role in the increased intracellular replication phenotype of the S. Typhimurium ΔsucCD strain, we constructed S. Typhimurium ΔaceA and ΔsucCD mutants and tested them for their ability to replicate within resting macrophages.
The FoldX force field was initially trained on a set of over 300 mutants and tested on a set of over 600 mutants as well as on 82 protein-protein interaction interfaces, with a reported correlation between calculated and experimentally determined folding and binding energies of 0.8.
We have investigated the contribution to virulence of various F. tularensis genes or pathways by creating transposon or deletion mutants and testing their virulence in the well-established mouse model.
However, making mutants and testing ATP hydrolysis rates seem straightforward now that the assay is up and running.
Future experiments will determine if increased cleaved tRNA fragments are observed in the RMTase mutants and testing these mutants under various environmental conditions may highlight additional roles for these genes in modulating stress responses.
In this study we constructed an intimin null mutant and tested its protective potential in vaccination-challenge experiments.
We generated viable eca mutant females and tested them for increased expression of four of the immune regulated genes that are up regulated in loj mutants (See Methods).
