Excel table of relative metabolite levels in bZIP63 mutants and p-values from T-tests.
In contrast, the combined mutation of the AhR and CREB motifs inhibited transcriptional activity very strongly in comparison to the individual mutations (p = <0.0001 vs the single AhR mutant and p = 0.0002 vs the single CREB mutant) (Fig. 5B).
Figure 2A shows that in any receptor mutant sets, the loss of ERS1 resulted in a reduction in total receptor gene expression (Student's t test for each isogenic mutant pair and P < 0.006) in adult rosette leaves.
Primers specific for the wild-type and mutant E- and P-selectin alleles, as described earlier (Frenette et al, 1996; Kim et al, 1998), were obtained from MWG-Biotech AG (Ebersberg, Germany).
Collection of deficiencies uncovering the second and third chromosomes of the genome, drivers, balancer stocks, smaller deficiencies, mutant alleles, and P-element insertions were obtained from the Bloomington Drosophila Stock Center (Bloomington, IN).
Still, the reduction of autophagosome area was completely rescued in these experiments (p = 0.02 for mutant and rescue, and p = 0.84 for control and rescue sample pairs, respectively), suggesting that Rack1 is required for efficient autophagosome formation (Fig. 2L).
We apply a Bonferroni correction for the multiple testing due to the 39 mutants and use a p value threshold of 0.05/39 = 0.001.
The superimposed structure of native and mutant P protein and its mutation was shown in Figure 3(b).
Furthermore, the inner and outer cortical perimeter of the femur mid-diaphyses was significantly smaller in Lrp4ECD mutants (Figure 3B, p<0.0001 and p = 0.002).
The signal intensities of PC 20 5/20 5) and PC 20 4/20 5) were higher in the wild-type than in the fat-1 mutants (p < 0.01 and p < 0.05, respectively, t test), whereas the signal intensities of PC 20 4/20 4), PC 20 3/20 4), and PC 20 3/20 3) were higher in the fat-1 mutants than in the wild type (p < 0.01 for all cases, t test).
