Sentence examples for mutants and certain from inspiring English sources

For example, insulin receptor daf-2 mutants have increased fat stores and a long lifespan [6], [15], while eat-2 mutands and certain growth conditions causing caloric restriction, lead to increased lifespan but have decreased fat stores [16].

Similarities have been observed between DAPT-treated embryos and Notch pathway mutants, and certain phenotypes in DAPT treated embryos can be partially rescued by microinjection of NICD mRNA [ 24].

Following UV mutagenesis, they used Nile red dye to screen for increased lipid production among the mutants and showed that certain mutants had an obvious increase in lipid production without a noticeable change in growth rate [ 5].

Roetschi et al. (2001), who first described the P. brassicae-Arabidopsis pathosystem, inoculated a variety of P. brassicae isolates on multiple Arabidopsis accessions and defence mutants, and showed that certain combinations result in compatible and others in incompatible interactions [ 1].

Finally, certain mutants of Hxk2 defective in catalytic activity retain full corepressor activity and certain mutants defective in repressor activity retain catalytic activity (Pelaez et al. 2010).

To test whether the observed effects were due to the negative charge introduced by MTSES or a steric effect of MTSES, we treated cells expressing wild-type OATP1B1 and certain mutants with the positively charged and membrane impermeable MTSET.

The complex that TIMELESS forms with TIPIN is distinct from the TIMELESS-PARP1 complex, since TIPIN does not co-immunoprecipitate with PARP1 (as detected by either immunoblot or mass spectrometry), and certain TIMELESS mutants, which are unable to interact with PARP1, still bind TIPIN.

Once incorporated into proteasomes, module 1 serves in effect as the 'lid core' sustaining a proteasome species prevalent in certain mutants and easily reconstituted from isolated components in vitro.

We show that low levels of e gr-1 suppress the extended lifespan of insulin signaling and germline mutants and reduce resistance to certain stresses, and that increased levels of egr-1 extend lifespan and confer resistance to stress.

Examples are: MutS may travel with the replication fork via its interaction with the beta-clamp (Lopez de Saro et al. 2006; Pluciennik et al. 2009); MutS alone can block recombination between diverged DNA in vitro (Worth et al. 1994); and certain mutS mutant strains have been reported to have an unexplained loss of viability (Boe 1990).

Other studies have shown that wild-type APP is not directly involved in modulating calcium stores but does mediate the increase in store size that is seen with certain PS mutants and PS deficiency [39].