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Fifty-five significantly modulated probe set IDs corresponding to 52 unique transposable elements were identified in at least one of the three mutants analyzed, based on the statistical difference (t-test, P<0.05, at alpha level, no multiple testing corrections applied) between homozygotes and heterozygotes for each genotype, combined with the minimum fold-change threshold (1.33, i.e. 33% change).
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In addition, germaria containing clonal mutant germline cysts were analyzed: based on the fusome morphology, the number of cells in a cyst and the location in the germarium, it was compared whether clonal germline cysts were of the same stage of differentiation as their non-clonal neighbors.
Contributing factors for the antimicrobial activity enhancement of N-terminally engineered mutants of cell-penetrating apidaecins were analyzed based on their cell-penetration efficiency.
Every doctrine is analyzed based on that.
Alternatively, data were analyzed based on absence/presence.
Using the ODD-luciferase transgenic mouse in concert with tumorigenic mouse mutants, we have analyzed base-line background signals from non-tumor-bearing mice, imaged a series of spontaneously developing mammary tumors over time, and conducted a proof-of principle study showing the feasibility of this model.
Assuming a median of 38 deleted gene models predicted at 80% TPR based on the 14 mutants analyzed (616 deletions/14 mutants, Table 2) and an coverage of ~38,000 gene models using Affymetrix Rice GeneChip® (based on version 5 of the TIGR annotation,, there is a 91% probability of detecting a deletion in each gene model at least once using only 3,000 mutants.
First, expression of the GABAergic specific marker unc-47 was unchanged in all mutants analyzed as compared to wild-type animals, based on the expression of the wyIs75 marker (Fig. 4A H).
Despite extensive mutagenesis, Sso7d mutants have high thermal stability; five of six mutants analyzed have melting temperatures > 89 °C.
Significantly, in 7/18 mutants analyzed, gross DNA rearrangements had occurred in the GMRα locus.
For better visualization, we generated a drought multi-trait matrix for all the BR receptor mutants analyzed in this study (Fig. 2d; Supplementary Table 1).
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