Sentence examples for mutants allowed us from inspiring English sources
In silico analysis of the ORFs within the transposons and construction of the corresponding knock-out mutants allowed us to identify the main regulatory protein involved in PAH degradation in Novosphingobium sp. HR1a.
Biochemical, genetic, and structural analysis of 20 mutants allowed us to determine that PduA K26, N29, and R79 are crucial residues that stabilize the shell of the 1,2-propanediol MCP.
Analysis of panels of viper-human NPC1 chimeras and point mutants allowed us to identify a single amino acid residue in NPC1, at position 503, that bidirectionally influenced both its binding to EBOV GP and its viral receptor activity in cells.
Analyses with U1-70K deletion mutants allowed us to identify two different regions as the speckle localization signals: the first 222 amino acids including the RRM, and amino acids 246 427, primarily comprising the arginine-rich C-terminal region.
Analyses of several intron-containing MIRs in SR protein mutants allowed us to ascertain our conclusion concerning the direct requirement of introns for proper miRNA biogenesis.
In the present study, two of these mutants allowed us to decipher the role of tissue-bound ACE versus secreted and circulating ACE.
To gain further insights into the effect of ATP binding on ARD stability, we used single-cysteine mutants, allowing us to specifically address the accessibility of a buried cysteine.
Vacuoles partially escaped auxin regulation in vti11 mutants, allowing us to assess the requirement of VTI11 function for auxin-dependent limitation of meristematic cell size.
This triple mutant allowed us to better understand the role gerPF and its orthologues were playing during germination.
Analysis of the mutant p38 proteins in which individual cysteines were added back to the 4CS mutant allowed us to assess the oxidation at each cysteine residue after PGJ2 treatment.
This latter mutant allowed us to evaluate the role of protein tagging in vivo under conditions that were more drastic than the point mutations affecting tag recognition described in previous studies.
