In contrast, rpb1-12xS2ACTD similar, similar to lsk1Δ and lsc1Δ mutants, displayed a characteristic sensitivity to LatA, and an inability to complete septum formation (Figure 6, A and B; Table 1).
As shown in Figure 6(A), both mutants displayed a characteristic spectrum containing both α-helical and irregular structures as the WT protein, but their intensities were much lower than the WT Tim9.
Although mlh3 Δ mutants show a characteristic 4 2 0 pattern of viable spores per tetrad indicative of nondisjunction (Ross-Macdonald and Roeder 1994; Hollingsworth et al. 1995; Hunter and Borts 1997; Argueso et al. 2003; Nishant et al. 2008; this study), neither mms4 Δ nor mlh3 Δ mms4 Δ showed this pattern.
Grown in standard field conditions in New Orleans, LA, the homozygous Li 1 mutant demonstrated a characteristic short fiber phenotype and other previously characterized pleiotropic characteristics.
Both a csn1 deletion strain (csn1Δ) and the csn1-E46 mutant exhibited a characteristic nuclear morphology during horsetail nuclear movements: the tip of the horsetail nucleus, which protruded from the bulk of the nucleus, moved back and forth within the cell, but the bulk of the nucleus did not follow this movement (Fig. 1A,B).
Increases in the fitness variance of asexual populations makes fixation of a beneficial mutant increasingly dependent on genetic background; only beneficial mutants that exceed a characteristic large size will have a high probability of fixing in populations with substantial fitness variance (Peck, 1994; Barton, 1995; Schiffels et al., 2011; Good et al., 2012).
Different disomic S. cerevisiae mutants also shared a characteristic transcriptional response (55).
The epidermal surfaces of both ems63131 and ms*6064 mutants contain stomata; a characteristic not normally found in anthers.
The cTnIR193H mutant alone exhibited a characteristic Ca2+-independent transition to shortened resting sarcomere lengths (Figure 4E and F) [22].
Consistent with the similarity to the histopathology seen in patients with IBD, some of the Hnf4α mutant mice displayed a characteristic phenotype with relapsing episodes of hematochezia and rectal prolapse (data not illustrated).
