Sentence examples for mutant worms indicating from inspiring English sources

However none of them was differentially regulated under anoxia in hif-1 defective mutant worms, indicating that they are HIF-1 dependent (Fig. 7).

Finally, we show that sDR further enhances the lifespan of eat-2 mutant worms, indicating that these two DR methods act additively to promote longevity.

A single LacI::GFP focus is detected in pachytene nuclei of wild-type, coh-4 coh-3, and spo-11 mutant worms, indicating that sister chromatids are tethered by SCC.

Protein levels did not change significantly between water-treated wild-type and ser-7 mutant worms, indicating that the ser-7 (tm1325 ) allele did not have a general effect on the total amount of protein in the worm.

Surprisingly, as shown in Fig. 6C, germ cells in this quadruple mutant proliferated in an uncontrolled fashion, just as they did in the puf-8; gap-3 double mutant worms, indicating that FBF is not required for the tumorous proliferation of the puf-8; gap-3 germ cells.

D tyra-2 mutant worms show a chemotaxis index comparable to that of wild-type worms.

The single vulva-like structure in ndk-1 ok314 ndk-1 ok314cates that a basal level of Ras/MAPK signaling needed for vulva induction still occurs in these mutants.

Number of worms indicated above each set.

Combining the results of three independent experiments (Fig. 2B), we found that bDR significantly extended the lifespan of WT (N2), aak-2 ok524), aak-2 ok524mu86) mutand worms (P < 0.0001), indicating that AMPK and FoxO are dispensable for the entire lifespan extension induced by bDR.

The eat-2 mutant worms also show similar switch in metabolism (Yuan et al., 2012).

Similar to what was previously reported (Viswanathan et al., 2005), we found that resveratrol still extended the lifespan of daf-16(mutantmutant worms (Fig. 3B; Table S5), indicating that resveratrol extends lifespan by eliciting an AMPK-dependent, FoxO-independent pathway.