Sentence examples for mutant worms expressing from inspiring English sources

To explore the possibility that the C. elegans DA transporter, DAT-1 might facilitate entry of the S. venezuelae factor, dat-1 mutant worms expressing GFP in DA neurons (dat-1; Pdat-1 GFP), Pdat-1 GFPeficient for DAT-1 [13], [22], whichexarenedeficientrodegeneration in response to the fortor.

(A ) Starvation assay of fcho-1 mutant worms expressing APA domains as single-copy transgenes.

Day-1 adult wild-type (and mutant) worms expressing the calcium-activity reporter GCaMP3 in neurons of interest were loaded with liquid NGM into a microfluidic chip.

In the case of rbr-2, the Caenorhabditis elegans ortholog of the H3K4me3 demethylase Jarid1a/Rbp2, mutant worms expressing a protein lacking the JmjC domain showed increased levels of H3K4me3, suggesting a global role for rbr-2 in balancing the effects of the cognate H3K4 HMTs (Christensen et al, 2007).

D tyra-2 mutant worms show a chemotaxis index comparable to that of wild-type worms.

tyra-2 mutant worms show defects in the suppression of feeding by 1-octanol, whereas overexpression of TYRA-2 under its own promoter or the zig-3 promoter, which is specifically expressed in the AIM interneurons, can rescue the feeding suppression defect.

Similarly, a significant, although partial rescue of the VPC induction defect associated with a let-23/EGFR hypomorphic allele (sy1) was observed in animals expressing the activating RAS-1G27dup mutant, but not in worms expressing the wild-type counterpart (Table  1).

For worms expressing Aβ1-42, mutant TDP-43 or FUS animals were counted as paralyzed if they failed tormove upon prodding with a worm pick.

Neurodegeneration in worms expressing transgenic human mutant Tau can be assessed indirectly, using phenotypes such as impaired locomotion and reduced lifespan, but also directly by visualising loss of neuronal cell bodies and neuronal processes in vivo.

Triple transgenic worms expressing human V337M mutant Tau protein (Paex-3::V337M Tau), a pharyngeal GFP marker (Pmyo-2 GFP) Pmyo-2 GFPeporter trandgene markinGFPhe cell bodies and preporter of all C. elegans GABAergic neurons (Punc-25::GFP) were compared witransgenel single Punc-25::GFP transgenic wormarking

A similar GFP RAB-3 enrichment effect was observed in worms expressinGFP RAB-3* mutant form of SNT-1, which contains a C2B domain that cannot bind Ca2+ (D383 and D385 wenrichmenteffecth alanines).