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Root mean square standardized effect [ 122] with sample size bias adjustment was calculated for each assay with the equation, and unbiased standardized pairwise mean differences (g) between wildtype PRE and each mutant within each assay were also calculated with the equation g = m j - m c MSerror × Γ 2 n − 2 2 Γ 2 n − 3 2 2 n − 2 2 [ 43].
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One aspect unifying mutants within each group is that members of one group, for instance Bcy1, Ira1/2 and Pde2, promote processes required under low glucose conditions.
It was suggested that the probability of a secondary mutation is enhanced only by the increase in cell number within the developing colony and selection acts only to favor growth of the new double mutants within each colony.
However, responsiveness to cytokinins is severely reduced and growth phenotypes could be observed in multiple mutants within each gene family [ 11– 13], indicating that the cytokinin TCS plays a central role in cytokinin responses in plants.
Cumulative curves of proportions of mutant viruses within each group over ARV exposure time were plotted for each subtype (B and C).
The process of tracing the distribution of the mutant allele within each family is still ongoing.
For the first approach we identified the ancestral allele from the sets of mutant alleles within each complex.
If the net control conductances are subtracted from the net mutant conductances within each treatment group, the conductances of D237A + K243C channels with and without DTT are comparable.
Average sleep for all lines is indicated on the X axis in increments of 25 min. The Y axis depicts the number of mutant lines within each group.
While many interventions affect lifespan in a sex-dependent way (Burger & Promislow, 2004), in our dataset female male lifespan profiles are consistent between wild-type controls and experimental mutant lines within each strain, that is, genetic background (Fig. S2).
The frequency distribution of a single-cell mutant load within each of the 10 cell pools corresponded to a binomial distribution, with a median value identical or very close to the mean value of heteroplasmy, in keeping with the random genetic drift mechanism.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com