Sentence examples for mutant with human from inspiring English sources

Complementation analyses of a rodent Rps4 knockout mutant with human RPS4Y2 gene would help to elucidate if this gene still conserves its original function or whether, according to the evidences presented in this work, it has acquired a functional specialization related to an extra-ribosomal function or even a new function.

Infections in chickens, common quails, red-legged partridges and turkeys may select for mutants with human receptor specificity.

In addition, the comparison of genome-wide expression data from the mouse mutants with human tumour datasets suggests that different human Wilms' tumour subtypes have different developmental stages of origin.

The ∼1080-fold ∼1080-foldt improvementlytin efficiency of the un-fused A199S/S287G/A328W/Y332G mutant is very catalyticthefficiencyly repofthe the ∼1000-fold improvement in the catalytic efficiency of the A199S/S287G/A328W/Y332G mutant fused with human serum A199S/S287G/A328W/Y332G

Immunohistochemistry on brain sections shows characteristic vascular human NOTCH3 accumulation in all four mutant strains, with human NOTCH3 RNA expression levels correlating with age at onset and progression of NOTCH3 accumulation.

It should be noted that often complementation of yeast deletion mutant with their human orthologues results in low levels of CoQ6 production compared to the human gene.

We agree that complementation of the Dictyostelium NF1 mutant with the human protein is a most desirable experiment.

3xTg-AD mice harbor human mutant PS1 (PS1M146V) along with human mutant APP (APPswe) and tau (tau P301L) protein.

Comparison of genome-wide expression data from the mutant mouse models with human tumour material of mutant or wild-type WT1 datasets identified the stage of origin of human WT1-mutant tumours, and emphasizes fundamental differences between the two human tumour groups due to different developmental stages of origin.

Consistent with the results of thrombin inhibition assays, only the tetra mutant showed interactions with human α- thrombin with dissociation constant (Kd) of 4 µM (Figure 7).

Each mutant was challenged with human αCGRP and cAMP production was measured (Table 1, Figs. 2 and 3).