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Under these conditions, a reduction in the activity of any one of the RTKs by a DN mutant will decrease signaling through multiple downstream pathways.
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Those "mutant" barcodes will decrease our ability to remove amplification artifacts in the reads.
In addition, having too many mutants pooled per barcode will decrease the detection sensitivity of the NGS method.
If the fitness of the mutant type is below the average fitness, its frequency will decrease.
In such cases, the non-reference mapping allele will decrease gradually towards 0% in the mutant pool upon getting closer to the causal variant, while increasing to 67% in the wild-type pool.
If the site has more than two mutant alleles or the depth is more than 2000X, the probability will decrease.
Maybe it will decrease".
Even so, the workforce will decrease.
D. It will decrease aggregate income.
C. Economy's output will decrease.
But we assume the number will decrease".
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