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In previous studies, an EcoRI mutant, which exhibited relaxed substrate specificity and cleaved both canonical and EcoRI star sites, was isolated.
Conversely, expression of a TβRIII mutant, which exhibited increased shedding, significantly reduced BMP-mediated Smad1/5/8 phosphorylation, migration, and invasion.
The increase in butanol production by ARTP was shown several times such as in a mutant which exhibited a 33% higher ABE solvents production and a 25% higher butanol production (12.53 g l−1 total ABE solvents, 4.9 g l−1 acetone, 13.71 g l−1 butanol, and 0.19 g l−1 ethanol) when compared to its wild type (Kong et al. 2016).
This differs from the slotu44c mutant, which exhibited thin filament defects in both slow and fast muscles (Fig. 5F).
Further evidence for a role in the control of actin turn-over is provided by the observation that L-plastin could substitute for yeast plastin in a Sac6 null mutant which exhibited defects in actin polymerization [21].
Interestingly, the E159A HCCS mutant, which exhibited enhanced function, also copurified with substantially less heme compared to WT HCCS.
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In the current study, we investigated the ghd10 mutant, which exhibits delayed flowering time, tall stalks, increased panicle length and an increased number of primary branches.
This induction of individual stomata opening by low fluence rates of blue light was disrupted in the phototropin1 phototropin2 (phot1 phot2) double mutant, which exhibits insensitivity of stomatal movements in blue-illuminated epidermal strips.
That MKS1 plays important roles in plant resistance responses is further supported by the recent finding that the snc4-1D mutant, which exhibits increased resistance responses, is partially suppressed by mks1 [19].
Finally, the IE4 S136A mutant, which exhibits the same subcellular localization as the wild-type protein (data not shown), appears also to be able to transactivate the reporter gene (Figure 7B, lane 6), suggesting that this phosphorylation site is not important in this mRNA export assay.
The CFTR-potentiator VX-770 stimulates passage of chloride ions from the G551D CFTR mutant which exhibits defective gating.
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