Sentence examples for mutant were substantially from inspiring English sources

Two-electrode voltage clamp studies of amantadine block also showed that both Kcv* and the T63S mutant were substantially less sensitive to the blocker than the wild-type channel (Figure 5).

However, wrky18 wrky40 and wrky18 wrky60 double mutants and the wrky18 wrky40 wrky60 triple mutant were substantially more resistant to P. syringae but more susceptible to B. cinerea than wild-type plants [ 27].

Likewise, CrPV IRES mutants analogous to the aforementioned G-rich mutants and another mutant in which three conserved bases were mutated (GGC mutant) were substantially decreased in their abilities to initiate translation.

Most samples showed the expected strong cross-reactivity, with high binding to wild type WNV E; however, the values for binding of the heterologous sera to the fusion loop mutant were substantially lower.

Interestingly, β-galactosidase activity in the agr, clpX double mutant was substantially reduced compared to the activity measured in the agr single mutant strain.

The amount of sphingolipids from EBs of infected cells overexpressing Rab14 negative mutant was substantially decreased compared to GFP and GFP-Rab14wt overexpressing cells assessed by TLC.

However, the binding affinity of the mutant was substantially lower than that of the wild-type protein.

These findings are consistent with the eBRET kinetic data suggesting that the Δ406-Δ427 mutant is substantially impaired in its ability to recruit β-arrestins.

However, in banana, resistance to Foc TR4 appeared to occur before colonization, as was demonstrated in the current study where the amount of spores attached to roots of the resistant mutant was substantially reduced.

Owing partially to advances in high-throughput sequencing technology and an additional focus on transposable elements in our analysis, the number of targets identified in the met1 mutant is substantially greater than that found by Lister et al. (2008).

Interestingly, the vascular extension phenotype is resolved in adulthood and the retinal abnormalities in the Nrp1 VEGF- mutant are substantially less severe than those described in Fantin et al., 2014 suggesting that some of the vascular defects reported in the Nrp1 Y297A/Y297A mutant are secondary to aberrant NRP1 protein levels rather than a lack of VEGF-NRP1 binding.