Sentence examples for mutant were reduced from inspiring English sources

As shown in Figure  3B, p300 acetylates lysine K193: indeed the levels of acetylation of the p63-K193R mutant were reduced.

We extended our analysis of H3K9me2 genome-wide and found that H3K9me2 levels in set1Δ clr3Δ mutant were reduced across the entire pericentromeric region.

Consistent with a previous report (Purcell et al., 2010), salivary gland sporozoites of this mutant were reduced by more than 90%, but sufficient sporozoites remained to expect these to transmit back to mice if fully infectious.

Although the photocurrent density of the S169A mutant was reduced in HEK cells, as compared to wild-type Chrimson (12 ± 4 pA/pF for S169A versus 90 ± 60 pA/pF for WT) (Supplementary Fig. 8b), its photocurrent size is comparable to the CrChR2 stationary currents measured in HEK cells under the same conditions (15 ± 7 pA/pF)22.

Treatment with 100 nM PDBu increased phosphorylation of both wild type and mutant TP receptors, but the extent of phosphorylation of the receptor mutant was reduced compared with the wild type.

In contrast, the Km value of CoA for K172A mutant was reduced by ∼3.5 times (Fig. 6D).

When expressed from a CEN plasmid to ensure physiological levels, binding of the S98A mutant was reduced strongly at ADH2 compared to wildtype Adr1 (Figure 4).

The thermodynamic stability of the I430A mutant is reduced relative to wt-KaiC; CD melting experiments indicate that the Tm of the mutant is lowered by about 3°C relative to wt-KaiC.

In contrast, the Prn-ko mutant caused similar disease severity relative to the wild type, however, colonization of the Prn mutant was reduced relative to the wild type during early and late infection.

Hapfelmeier et al reported that the residual inflammation caused by infection with a SPI-1 mutant was reduced significantly if mice had a mutation in MyD88, which abrogates most signaling through TLRs [27].

The activity of the Phe300Gln mutant is reduced >200-fold.