By analyzing the UGD double mutant, we expect a significant decrease of UDP-sugars downstream of UGD.
Since Cora was shown to control the amount of GluRIIA, and since the amount of postsynaptic Cora was largely reduced in dg mutants, we expected to see a decrease in the amount of GluRIIA subunit present in the postsynaptic glutamate receptors.
Given the reduced number of cells in the pLLP of yap1 morphants and mutants, we expected a similar result.
Since tapetum cells are either absent or dysfunctional in the mutants, we expected that the expression of tapetum-related genes would reduce significantly.
Since the HIF-1 dependent globin genes were not induced by anoxia in daf-2 mutants we expected that DAF-16 would not mediate or rather oppose their induction upon anoxia.
Especially for various mutants, we expect that even if knock up/down or mutant genes can influence normal gene expression profiles, the proteins affected by them may still involve in similar stringent pathways and hold similar co-expression trends or patterns.
Based on our structures, we additionally designed a R81A/Y87F double mutant that we expected to have the strongest effect.
Since DEX treatments led to a dramatic reduction in flowering time of the 35S::GI-GR gi-2 mutant plants, we expected that potent flowering time activators such as FT would be induced by DEX application.
Since age-1 and daf-2 mutants share many phenotypes, we expected that the age-1 and daf-2 transcriptomes would be similar.
Because we had previously found that APAs lacking KCNJ5 mutations, with histological features resembling ZG, had a different gene expression profile from KCNJ5-mutant ZF-like APAs, we expected to find an overlap with genes upregulated in the ZG when compared with ZF.
