Sentence examples for mutant was sufficient from inspiring English sources

Unlike T50A or S389A, expression of the S142A mutant was sufficient to cause TFEB nuclear translocation.

In regards to mutations themselves, the R882H DNmutantutant was sufficient to promote tumorigenesis in an IL-3 dependent transformation assay in leukemic 32D cells (Yan et al., 2011).

Neither the C79A nor the C308A single mutant was sufficient to prevent the dimer formation.

Addition of the CCISL motif to the C-terminal truncation mutant was sufficient to restore normal Rab25 localization.

Overexpression of wild-type Sirt1, but not the deacetylase-dead mutant, was sufficient to induce autophagy in ECs.

Strikingly, restoration of mannan core branching in the mptC mutant was sufficient to fully complement the in vivo phenotype in embryos.

The RB-K530A (K) mutant is sufficient to inactivate the E2F-binding pocket, whereas the RB-N757F (N) mutant is sufficient to inactivate the LxCxE-binding pocket.

These results confirmed that cleavage of the inhibin α-subunit occurs at the consensus cleavage motif and that mutagenesis of only the last arginine (the RARA mutant) is sufficient to abolish C-terminal proteolytic processing.

Wild-type MYO2 expressed in myo2Δ cells, or in the myo2Δ vps45Δ mutant, is sufficient for cell viability.

Taken together, these data suggest that the residual SUMOylation of Ago2 observed for the K402R mutant is sufficient to maintain RNAi activity of Ago2.

Accordingly, we show that tethered NOT1 and a catalytically inactive POP2 mutant are sufficient to cause PABP dissociation from bound mRNAs in the absence of deadenylation.