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Rahman et al. also examined OGT and OGA null mutant interaction with other known insulin-like signaling dependent phenotypes and found that the OGA mutant was resistant to oxidative stress, while the OGT mutant reduced stress resistance in a daf-2 mutant background.
Interestingly, due to low affinity, the G122H/Y124Q/S125T mutant was resistant to sub-millimolar concentrations of OPs.
Conversely, our Glu378 insertion mutant was resistant to aldicarb (Figure 5) consistent with the observed reduction in fusion events in chromaffin cells (Figure 3).
We were surprised that the dna2Δ pif1Δ mutant was resistant to X-rays (Figure 1, the sensitivity of mre11Δ and mre11Δ pif1Δ are shown as controls), since several dna2 hypomorphic mutants are sensitive to IR [31], [36].
Again, the C1238V mutant was resistant to PEITC.
In Arabidopsis, fad7fad8 double mutant was resistant to high temperature [ 67].
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In addition, ral1 mutant is resistant not only to Al but also to Cd.
These results indicate that Ser214, together with the adjacent dicysteine motif C212/213, are equally essential in mediating the arsenic-PML binding, consistent with the data that S214L mutant is resistant to AS2O3-induced degradation.
We have previously determined that this Casp8RN mutant is resistant to HIV-1 protease cleavage [3].
If a mutation is present in a combination of two drugs, then that mutant is resistant to each drug.
This table indicates if a mutant is resistant to each concentration of each drug; this is marked by a "+".
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