Sentence examples for mutant was modified from inspiring English sources

To investigate how DbpA and DbpB contribute differently to the overall virulence of B. burgdorferi, a dbpAB mutant was modified to overproduce the adhesins.

None of the other genes in imipenem-selected mutants were modified, rearranged or acquired by horizontal-gene transfer upon imipenem exposure compared to their parental strains.

The constructs for expression of human AdoMetDC and mutants were modified from those described previously (18, 32− 34) to place the (His 6 tag at the carboxyl end of the protein replacing the C-terminal -QQQQQS sequence.

For the heterozygous assay, the mutant atx7-100-A-eGFP atx7-100-A-eGFP atx7-100-A-eGFP atx7-100-A-eGFPhe red fluorescent protein from pDsRED-monomer-N1 vector (Clontech).

Although vesicle release was similar in WT cells and in the snf7 mutant, the abundance of 35 proteins was modified in the mutant vesicles, suggesting that defects in MVB formation also affect extracellular vesicles in fungi.

A PCR amplification reaction targeting the deletion breakpoint in normal, heterozygous and homozygous mutant individuals with the Filipino deletion was modified to detect simultaneously the normal and mutant alleles using three PCR primers 45F: 5' TCA GAA GCA GAG CTA CTC AG 3'; 45R1- 5' GTC TAT GCA GGT GTG TAG ACA 3' and 45R2: 5' CAT TTA GCT CCC ACA CTC CT 3'.

Furthermore, the PP2A-dependent regulation of the subcellular localization was modified in the mutant GLI3 proteins.

Mutant atxn7 (Calso00 (alsobtaineded from A Brice) was modified to replace the G residue of the SNP (rs3774729) with the mutant A allele.

This procedure was modified slightly for RcPutA mutant RcPutAE1012A.

We then tested whether the gut homeostasis was modified in a Toll-9−/− mutant.

We previously demonstrated that a fragment of mutant HTT is modified by Small Ubiquitin-like MOdifier 1 (SUMO-1), and genetic reduction of SUMO in Drosophila-expressing mutant HTT exon 1 is protective (Steffan et al., 2004).