Sentence examples for mutant was effective from inspiring English sources

These evidences suggest that the IRESatt772 mutant was effective in reducing translation efficiency.

The R21A mutant was effective, unlike R49A mutant, at inhibiting such apoptosis.

Our data show that TIMP-1-mediated neuroprotection is, at least in part, MMP-independent and an addition into its non-classical functions because the T2G mutant was effective as wild type TIMP-1; but other MMP-inhibitors, TIMP-2 or -3, did not protect neurons from STS-induced apoptosis.

It was found that, in addition to culture pH [Kusaka et al. Appl Microbiol Biotechnol 1997 47 140], other variances such as culture temperature, host strain and use of mutants are effective in changing polymer molecular weight.

ERα mutants were effective as wild type ERα in modulating alternative splicing in the presence of E2.

Alternately, in R. leguminosarum, braC mutants are effective in alanine uptake (but are lacking in the uptake of the other three amino acids) [ 38].

Overall, these results suggest that aberrant expression of WT or catalytically inactive (C277S) TG2 mutants is effective in promoting the EMT and that the GTP-binding function of TG2 is critical to this effect.

Our findings confirmed that the recombined RBP-J allele was a true null allele and that inhibition of the Notch/RBP-J pathway in the double-mutant mice was effective.

Comparison with the effect of wild type with aspartate (D; to mimic phosphorylation) and alanine (A; non-phosphorylatable) mutants of telokin showed that the S13D mutant was more effective than wild type in relaxing smooth muscle at constant calcium.

Co-immunoprecipitation studies revealed that the SnoN (EdA) mutant was as effective as the wild type SnoN in associating with PIAS1 (Figure 7A).

The E164A/E165A αB-crystallin mutant was more effective (p<0.01) at inhibiting the increase in ThT fluorescence compared to the wild-type protein.