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In addition, this mutant was capable to convert secondary and cyclic alcohols, at a rate not detected in the other isoforms.
However, the RD mutant was capable of fermenting a mixture of glucose and xylose with stable yields (0.35 g g−1) and productivities (0.52 g L−1 h−1) during the repeated-batch fermentation.
The remaining mutants exhibited a range of replication efficiencies; however, each mutant was capable of replicating in the presence of concentrations of DSB that effectively inhibited wild-type HIV-1.
We concluded that the W242L mutant was capable of forming heteromers with WT subunits.
We thus analyzed if the Cry1Ab-D136N/T143D mutant was capable of blocking the toxicity of other Cry1 toxins when mixed at sub-stoichiometric ratios.
We first introduced the N51S mutation into NUP98-HOXA9 and showed that the mutant was capable of regulating transcription in a myeloid cell line without significant binding to DNA.
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Importantly, the invasion rate of KO-AMA1 increased in continuous culture to reach 20% after 12 months, suggesting that the mutant is capable of moderate adaptation to bypass the deleterious AMA1 inactivation (Fig. 5d).
Nevertheless, the RB-KN mutant is capable of reducing etoposide-induced apoptosis.
In addition, bloodstream forms of the mutant were capable of differentiating to the procyclic form without a detectable growth phenotype.
Unlike the null allele of Wu that could not generate mutant somatic clones in the wing discs, our mutant is capable to support limited cell proliferation (Figure 7D).
This is consistent with a report by Onishi and colleagues, that a constitutively active STAT5 mutant is capable of inducing IL-3 independent growth [31].
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