Your English writing platform
Free sign upExact(3)
The mutant virus that included "Spanish Flu -like low-pH-stable NA showed remarkable replication in comparison with the mutant virus that included low-pH-unstable N1 NA.
Our data showed that the activation of NF-κB is not restored upon infection with the mutant virus that does not express the ORF47p (ROka47S) compared to infection with the WT virus.
Ad5/ts369 is an L1-52/55K temperature-sensitive mutant virus that is blocked at an intermediate stage when grown at the non-permissive temperature of 39.5°C [29].
Similar(57)
It's evolution at its finest: The more opposite the immune systems, the greater the chance of producing bionic children who can withstand those ultra-contagious mutant viruses that are supposedly going to force us all into biohazard containment camps in 2016.
Specifically, replacement R55W in 2C was repeatedly found in several mutant viruses that had regained competence in plaque development.
Therefore, all HSV-2 ICP0− mutant viruses that were IFN-sensitive in cell culture (Fig. 2C) were also avirulent in mice (Fig. 5D).
In contrast, recombinant HSV-2 ICP0− mutant viruses that were IFN-sensitive (Fig. 2, 3) were also avirulent in ICR mice (Fig. 4, 5).
HSV-2 ICP0− mutant viruses that included deletions of ICP0's RING finger domain were avirulent, but did not elicit consistent protection against HSV-2 (Fig. 6B).
Thus, HSV-2 0ΔRING and 0ΔNLS were the only HSV-2 ICP0− mutant viruses that were IFN-sensitive and retained the capacity to replicate with reasonable efficiency in cells that did not provide wild-type ICP0 in trans.
In this regard, IRF3 activation was examined following infection with HSV-1 mutant viruses that restrict ICP0 expression to either the nucleus (R7914; F strain) or the cytoplasm (D8; 17strainrain) or following HSV-1 infection in the presence of chemical inhibitors that restrict the expression of ICP0 within the nuclear compartment.
All mutant viruses that lacked one or both forms of the NSm proteins were produced at reduced titers.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com