Sentence examples for mutant variant with from inspiring English sources

This mutant variant with increased resistance did not spread further.

Indeed, as expected, the interaction of this mutant variant with Rsp5 was impaired, although not abolished, relative to the wild-type control (Figure 1E), implying that the motif mediates in part the recruitment of Rsp5.

Interestingly, in this study, we also observed an association of this mutant variant with lower Karnofsky performance scores after therapy for trend as a further possible indicator of the relevance of this variant for MTX toxicity.

In contrast, only mutant variants with defects in the bulky second cytoplasmic loop serve as substrates for the cellular ERAD quality control system.

Other reports of SNP variants in miRNA precursors where the mutant variant correlates with an increased risk of cancer include miR-196a-2 miR-196a-2 miR-196a-2 cander, miR-499a-2 in head and neck cancer, whilst increased mature levels of miR-146a can lead to an earlier onset of breast and ovarian cancers.

In this study, three patients were identified as being infected with oseltamivir-resistant mutant variants (two with NA-H275Y and one with NA-N295S) (Figure 2).

HEK293T were transfected with expression constructs for wildtype Taspase1::Flag and the dnTASP1::Flag mutant variant in conjunction with an AF4 MLL expression plasmid.

Indeed, in the current study, seven of the subjects with the mutant variant failed to respond to SSRIs, and the other two required extremely high doses.

It is reported that the deletion or replacement of gene creA with truncated mutant variant enhances the cellulolytic enzyme production capacity in T. reesei [ 21].

A previous study of the interaction between this chemokine and glycosaminoglycans led to the development of a mutant sequence variant with reduced affinity for HS (18).

The enhanced susceptibility of these mutant variants was corroborated with the simultaneously abrogated efflux of substrates.