Exact(9)
The least frequent allele, or mutant type, is generally encoded as '1', as opposed to the most frequent allele, or wild type, generally encoded as '0' [3].
If the fitness of the mutant type is below the average fitness, its frequency will decrease.
In both cases, the mutant will go extinct and the average fitness will remain unchanged, since a mutant type is supposed to arise with a small amount.
The probability that a resident type i produces a mutant type is μ x i W i x / W ¯ x, where i = 1,2,3,…, n.
This yeast mutant type is very sensitive to Zn deprivation because of the mutation of their both high (ZRT1)- and low (ZRT2 -affinity ZRT2 -affinityems [ 19, 20].
The backbone was the same for the wild-type and the variant structures (shown in red color), whereas the side chain which was unique for wild and mutant type is shown in black color.
Similar(50)
The current approach is demonstrated with the identification of a single-base mutation in artificial codon CD17 of the β-thalassemia gene, and the wild type and mutant type were discriminated successfully.
The first mutant type was unable to use nitrate ('NO3 loss mutant'), and the second was unable to use either nitrate or nitrite ('NO3/NO2 loss mutant') (Fig. 1B).
When wild-type and mutant type were mixed, mutant DNA could be repeatedly detected in the percentage of 1∼10% (Figure 4E).
The payoff entries to describe the mutant type are random variables obeying a probability distribution which is related to the fitness of the parent type.
Owing to the mismatched nucleotides, a BST X1 site was created in the PCR product (200 bp) if wild type sequence (but not mutant type) was amplified.
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