Sentence examples for mutant to wild from inspiring English sources
Mutation can occur in two directions; mutation from wild type to mutant is called a forward mutation, and mutation from mutant to wild type is called a back mutation or reversion.
Thus, NTD125 shifted the equilibrium from the mutant to wild type and behaved as a chaperone-like peptide.
In vivo ELISA and immunoprecipitation analysis of NTD125-transfected cells revealed that NTD125 shifted equilibrium from p53 mutant to wild type under heat stress conditions.
NTD125 thus stabilized and induced nuclear translocation of cytoplasmic p53 supporting earlier observations that nuclear translocation of p53 could result in a change in the conformation from mutant to wild type [29] [31].
Nuclear translocation of p53 can result in a change in the conformation from mutant to wild type [29], [30] and genotypically WT p53 behaves as tumor suppressor in activating p53-downstream genes [28].
Most of the pathogenic mtDNA mutations are heteroplasmic (a mixture of both mutant and wild type mtDNA in the same cell or tissue) and the disease manifestations or clinical expression depends on the ratio of mutant to wild type mtDNA [7].
Depending on the ratio of mutant to wild-type mtDNA, known as heteroplasmy, mitochondrial defects can result in a wide spectrum of clinical manifestations.
Genetic crosses of the hydA1-1 hydA2-1 mutont to wild-type cells allowed us to also isolate the single hydA1-1 mutant.
Protein secondary structure and stability (using circular dichroism spectropolarimetry), self-association (using analytical ultracentrifugation), and DNA-binding measurements revealed RTP.C110S to be the most similar mutant to wild-type RTP.
Low-level, nonspecific amplification was detected in reactions containing a high copy number of plasmid standards and in specimens from patients not known to have myeloproliferative neoplasms, necessitating the use of a laboratory-established mutant to wild-type cutoff.
The competitive index (CI) is defined as the output ratio of mutant to wild-type bacteria divided by the input ratio of mutant to wild-type bacteria [21].
