Sentence examples for mutant to reduce from inspiring English sources

Heme staining of whole cell extracts revealed no differences in cytochrome expression compared to wild type (data not shown) confirming that the inability of a cymA mutant to reduce fumarate was due to the absence of CymA and not differential expression of the Mtr pathway.

If possible, find flanking markers that are each ∼5 cM or less from the mutant to reduce double recombination events that will complicate later mapping.

This complementation restored the ability of this mutant to reduce Fe(III -citrate to the level of 83% of that by the wt.

Similarly, complementation of Δ ombB-omaB-omcB-orfS-ombC-omaC-omcC with the ombB-omaB-omcB gene cluster increased the ability of the mutant to reduce ferrihydrite by twofold after 312 h (Fig.  2C).

We also introduced the gene cluster ombB-omaB-omcB into Δ ombB-omaB-omcB-orfS-ombC-omaC-omcC and then tested the impact of complementation on the ability of this mutant to reduce Fe(III -citrate.

In our first biochemical assay, we assayed the ability of DsbG* mutants to reduce disulfide bonds using an insulin reductase assay.

Several integrase mutations, including N155H, Q148R and Y143R have been shown in site-directed mutants to reduce raltegravir susceptibility more than 10-fold.

The ability of the soluble NaTrxh mutants to reduce insulin disulphide bonds was evaluated as previously described [ 7] and compared with the reductase activity of the wild-type recombinant NaTrxh [ 22].

Because the failure of CaM mutants to reduce TMEM16A calcium sensitivity could conceivably be due to the inability of the mutant CaM molecules to sufficiently displace endogenous CaM from the putative TMEM16A-CaM complexes, we further clarified the role of CaM in TMEM16A-CaCC gating by conducting four additional experiments to manipulate the potential interaction between CaM and TMEM16A.

Differentially expressed miRNAs may also target HTT transcripts as a response to mutant HTT to reduce HTT transcriptional levels and limit toxicity.

Resection mutants fail to reduce transcription around the DSB.