Sentence examples for mutant the first from inspiring English sources

Bungarus fasciatus acetylcholinesterase (BfAChE) was engineered to acquire organophosphate hydrolase (OPase) activity by reproducing the features of the human butyrylcholinesterase G117H mutant, the first mutant designed to hydrolyse OPs.

The stability of mito c-Photina function made this mutant the first choice for transfection into mES cells.

In the toz mutant, the first division of the zygote is normal, but the longitudinal division planes of the apical cell are generally replaced by transverse divisions [ 28].

For GFP-dFMRP-ΔKH mutant, the first PCR fragment was amplified with the GFP-EcoRI F and dFMRP-BamHI R672 oligos, and the second PCR fragment amplified with the dFMRP-BamHI F1012 and dFMRP-XbaI Rend.

Collectively, the experiments suggest that Δ122p53 (and Δ133p53 α) has two kinds of interaction with p53 (FLp53 or mutant)—the first is to interfere with normal p53 degradation and the second is to modulate p53 dependent transactivation.

Similarly, mutant rps17b-S3 is a result of a 4-nucleotide-segment substitution in the 3mDB1 mutant (the first segment of lower case letters represents the original 3mDB1 mutation).

In the Arabidopsis fwf-1/arf8-4 muthethirde third whorl organs have an inhibitory effect on parthenocarpic silique development, [ 2].

To create a trapping mutant, the second cysteine of the CXXC motif was replaced by serine (C35S).

In the double-flowered gentian mutant, the fourth-whorl pistil was not converted into petals, possibly because of the function of GsAG2.

Here we reveal key components of the degradative route of V247M α-sarcoglycan mutant, the second most frequently reported mutation in LGMD-2D.

It is worth noting that in this mutant the second activator was Fru6P, with a specificity constant of 5.4 mM-1, a different trend compared to OtaS/OtaL and OtaS where the second activator was FBP (Table 1).