Sentence examples for mutant that would from inspiring English sources
Normal kidney cells were stably transfected with both wild type Tensin3 as well as a Tensin3 mutant that would potentially abolish any phosphatase activity.
We tested this structure in the same way, by introducing destabilising mutations independently in both arms at the base of stem 2' (creating mutants p2luc-BM2A1' and p2luc-BM2A2') and preparing a double mutant that would yield a pseudowild-type structure, which would be expected to exhibit BM2fluc synthesis p2luc-BM2A1'/2' p2luc-BM2A1'/2'
What is missing for sure is a mutant that would be mechano-insensitive and in which STM expression pattern at the boundary would be less robust.
But there is nothing to compare a synthetic effect with, such as another mutant that would provide a longer inter-SPB distance when coupled with a chl4 deletion.
Analysis of the Y341A mutant of human tyrosyl-tRNA synthetase, a functional mutant that would not crystallize, with HDX MS and SAXS revealed conformational changes essential for activation via uncovering of an internal tripeptide sequence.
As a final remark, we note the possibility of a superior mutant that would undo the decoupling between inducer and carbon source and become responsive to Pgal, so that (6) Z reg (P ) = Z opt (P ) However, none of the evolved populations here was found to be induced by Pgal.
Mutants that would have taken days to identify using old methods were spotted by Dr Siuzdak's group within 20 minutes.Dr Siuzdak's team has already formed collaborations to study mutant forms of other viruses, including hepatitis B and HIV, the virus that causes AIDS.
We thus predict that it should be possible to identify CIII mutants that would be dominant negative due to formation of inactive CIIImutant-CIIIwild-type hetrooligomers.
We then used this library to search for Kcv mutants that would be resistant to either blocker by conducting selections for Kcv mutants that could rescue the potassium-deficient yeast strain in the presence of barium or amantadine under conditions where channel function was required for survival.
Other groups started to establish screens to look for mutants that would affect organ development.
We had reasoned that there would be many autosomal genes in female Smchd1 mutants that would display deregulated expression that was secondary to failure of X inactivation.
