Sentence examples for mutant that specifically from inspiring English sources

In keeping with this, we demonstrate that a PS2 mutant that specifically disrupts myofibril formation is unable to mediate proper localization of nonmuscle myosin-II at the muscle termini.

Here, we identified a unique unc-13 mutant that specifically deletes the C2A domain of UNC-13L.

These data show that PYMΔNΔC-FLAG functions as a dominant negative mutant that specifically disrupts PYM-dependent ORF57 interactions.

Next, to examine the inhibitory activity of CysC treatment on CatB activation by mutant SOD1 expression, we created a W106G CysC mutant that specifically lacked the inhibitory activity against CatB.

To investigate this, two graduate students in my lab, Bill Winston and Christina Molodowitch, isolated mutants that specifically disrupted dsRNA mobility (Science, PDF).

In this study, we identified and characterized rice mutants that specifically disrupted the development of palea, one of the outer whorl floral organs.

To establish whether anthrax toxins were responsible for the downregulation of IL-8, the most potent and strongly affected neutrophil chemokine, we utilized isogenic mutants that specifically lacked LF (ΔLF), EF (ΔEF) or both anthrax toxins (ΔLF/EF).

In an attempt to screen for the phiC31 mutants that specifically recognized and integrated into target sites more efficiently, the technique of DNA shuffling was employed, and it had obtained many mutants, which with increased integration efficiency in human cells [36], [37].

The new alleles represent partial loss-of-function mutants that specifically disrupt muscle arm development.

The identification of point mutants that specifically abolish these interactions could facilitate a further dissection of NCOA4 function.

Upon expressing UNC-45 mutants that specifically impede UNC-45 chain formation, a dominant-negative effect was observed in wild-type worms.