The wild-type Xcc strain 8004 was subjected to Mariner transposon mutagenesis, and mutants that gave reduced ELISA signals and contained a single and unique transposon insertion (determined by Southern analysis) were found from screening ∼5000 colonies.
Interestingly, all alleles showed increased levels of the Blood and HetA retrotransposons to some extent; however, those spn-E mutants that gave the strongest developmental phenotypes showed considerably higher levels of HetA and Blood compared with the other alleles.
People from time to time have been born with mutant genes that gave them a slight reproductive edge, one that their offspring enjoyed as well.
The mutant Cys426 protein, that gave the best diffracting crystals, was used for derivatization with mercury and platinum compounds both by co-crystallization and by crystal soaking.
In the one case of a LKB1-mutant lung tumor that gave rise to liver metastasis, the metastasis scored negative for the mutation.
Recent evidence suggests that stem cells may be the source of mutant cells that give rise to tumors and maintain their growth [24].
The models all wore enormous encrusted nose rings that gave them mutant features.
There are eight possible combinations of background state and mutant that give rise to a novel regulatory connection: (1) a→A/f→f-, (2) a→A/f→f+, (3) a→A/m→m-, (4) a→A/m→m+, (5) f→f-/a→A, (6) f→f+/a→A, (7) m→m-/a→A, (8) m→m+/a→A (Table 2).
Heterozygous Eda (female) mice were identified morphologically by the distinctive striping of the coat that gave these mutants their original name, 'Tabby'.
Inspired by the civil rights movement in America, Lee and Jack Kirby created the X-Men comic universe, a world in which some people, known as mutants, were born with a gene that gave them special abilities but also often made them look different than typical humans.
