Sentence examples for mutant that binds from inspiring English sources

Additionally, the ribbon organization of the Golgi is disturbed in KIF1C siRNA cells, a phenotype that can be suppressed by KIF1C expression, and not by the loop 6/10 mutant, but, significantly, can be rescued by a KIF1C mutant that binds Rab6 but not microtubules.

In contrast, expression of the KIF1C loop 6/10 mutant that binds microtubules but shows diminished Rab6A binding did not protect the Golgi from nocodazole-triggered ribbon breakdown.

Thus, pre-activated mouse arrestin-1-3A muthat that binds Rh* with high affinity was used (Song et al., 2009b; Vishnivetskiy et al., 2013).

This hypothesis is strongly supported by the results obtained from the expression in the HaCaT model system of a HPV-16 E7 mutant that binds GSTP1 less efficiently.

To assess proper GTP hydrolysis, Ras and Ras(G12V), a mutant that binds GTP, but is deficient in GTP hydrolysis were used to validate the assay [45] [47].

For this purpose, transient transfection assays were performed in the presence of wildtype CHD4 or CHD4del(1–1280), a dominant negative CHD4 mutant that binds to Nab2 but lacks the ATPase domain required for nucleosome remodeling [27].

We will use ribosome display to select Cyt1Aa mutants that bind other Cry toxins as a way to develop tools for improving Bt Cry toxicity against specific insect targets.

Only the mutants that bound to YopJ, P15 and P16, were acetylated by YopJ (Figure 6B).

Nine rounds of FACS were used to isolate mutants that bound with high affinity to αvβ3 integrin (Table S2).

More recent studies described 2 C3 mutants that bind CFB with higher affinity, resulting in a more stable C3 convertase complex.

Expression of activated Ras effector domain mutants that bind Raf, PI3K, or RalGEF are sufficient to induce the anchorage-independent growth of the human mammary epithelial cell line HME16C and are associated with up-regulation of EGFR ligands.