Sentence examples for mutant studies have from inspiring English sources

Many mouse mutant studies have serious methodological problems leading to fatally flawed scientific conclusions, causing a waste of time, effort, and research resources, and leading to ethical problems because of the unnecessary use of live animals for flawed studies.

In addition, mutant studies have identified several genes that are required for this complex behavior [32].

These mutant studies have suggested the specific roles of each ligand in various Notch-mediated fate decisions.

Mutant studies have revealed the interaction of sugars and hormones [ 18, 19] and the concept of a carbon:nitrogen 'matrix effect' in metabolic regulation [ 20].

Mutant studies have provided further evidence for the key role of transcriptional regulation of carotenoid biosynthetic genes in controlling carotenoid production in tomato and pepper.

Although mutant studies have provided valuable insights, lack of X-ray crystallographic data has hampered definition of BuChE P-site details.

As mentioned above, PolyP granules may interact with polyamines (note that even if those isolated from E. coli did not contain calcium the phoU mutant studied had 1000-fold higher levels of PolyP than the wild type [ 62]).

Human genetics and mutant animal studies have identified a complex molecular regulatory network that controls tooth development, which is mediated by evolutionarily conserved transcription factors and signaling pathways that are shared with development, maintenance, and regeneration of many other organ systems across different species.

In the case of gain-of-resistance mutants, several studies have provided useful insights into the regulation of defense (Feys and Parker 2000; Frye and Innes 1998; Yu et al. 2000; Thatcher et al. 2005).

Consistent with our findings with domain-deleted mutants, prior studies have demonstrated that CRT tertiary conformation is critically important for its biologic activity [25].

To address the role of Erk and Src phosphorylation of cortactin, we used both phosphorylation-mimicking and non-phosphorylatable mutants; previous studies have used only the former [ 23].