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Mutant strains lacking electrically conductive pili, or pili-associated cytochromes participated in DIET only in the presence of carbon cloth.
In addition, the mutant strains lacking DnaJ and CbpA which are co-chaperones that stimulate the ATPase activity of DnaK showed the similar RpoS solubility compared with wild type (Fig. 3a and Supplementary Fig. 4).
Similarly, C. albicans mutant strains lacking calcineurin B are markedly hypersensitive to terbinafine and fenpropimorph.
C. albicans rbp1/rbp1 mutant strains lacking a homolog of the FK506-rapamycin target protein FKBP12 were found to be viable and resistant to rapamycin and its analogs.
The calcineurin inhibitors cyclosporine A (CsA) and tacrolimus (FK506) are dramatically synergistic with azoles, resulting in potent fungicidal activity, and mutant strains lacking calcineurin are markedly hypersensitive to azoles.
lic4 mutations also exacerbate the Li+-sensitive phenotype of hal3 mutant strains, and overexpression of either Lic4 or Hal3 suppresses the salt sensitivity of mutant strains lacking calcineurin, Hal3, or Lic4, either singly or in combination.
Similar(25)
Oscillatory behaviour in the tryptophan operon of an Escherichia coli mutant strain lacking the enzyme-inhibition regulatory mechanism has been observed by Bliss et al. but not confirmed by others.
This was confirmed by showing that a mutant strain lacking HBHA did not bind the heparin tip.
The normal B. fragilis easily outcompetes a mutant strain lacking the pathway for making and scavenging L-fucose.
Experimental proof of the key role of the irp gene in the grazing resistance was evidenced with a mutant strain lacking this gene.
A mutant strain lacking a functional katE gene was constructed and used to demonstrate that KatE is the major catalase induced in Xac during the stationary phase of growth.
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