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Additive effects on ADH1 TSS distributions in Pol II-GTF mutant strains indicate that individual defects of each allele are present in the double mutant strains.
Competition assays between the ancestral strain and either of two mutant strains indicate that both mutants out-compete the ancestor at high temperature, but the relative frequencies of each phage remain the same at the control temperature.
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Similarly, lic4 mutations increase the Li+ sensitivity of both wild-type and calcineurin mutant strains, and reduce expression of pmr2A in calcineurin mutant strains, indicating that calcineurin and Lic4 may regulate parallel cation homeostatic pathways.
Peaks on DF curve at 20 50 ms, and 1 s were reduced in mutant strains, indicating a decrease in the formation of electrical and proton potential differences across the thylakoid membrane.
Analysis of a series of C. elegans mutant strains indicates the intermediates are produced by NUC-1, a DNase II endonuclease.
Transcription of the dnaA and dnaC genes was increased at the non-permissive temperature in the respective mutant strains indicating auto-regulation of both genes.
However, the lack of a significant number of genes showing differential expression between wild-type and H2B K37A mutant strains indicates overall that H2BK37me2 alone does not play a major role in regulation of transcription on a genome-wide level in budding yeast.
Cell cycle profile analysis showed little difference between the strain harboring WT H2A and any of the mutant strains, indicating that the observed differences in chromatin compaction are not due to altered cell cycle profiles.
Intensive H2O2 and paraquat challenge tests showed that lifespan was only extended in Oregon-R wild type flies but not in SOD n108 (deficiencyin SOD) or Cat n1 (deficiency in Cat) mutant strains, indicating that the prolongevity activity of blueberry was mediated by its enhancement on endogenous antioxidant system.
Disappearance of the three bands observed in the wild-type in six of the seven mutant strains indicates that irradiation caused significant changes from wild type in the regions amplified by this VNTR primer in the wild-type, and the appearance of five completely new bands in this region suggests that different mutations were caused in the genomic DNA of wild-type Y.
Genome-wide chromatin immunoprecipitation of Wor3 and gene expression profiling of a wor3 deletion mutant strain indicate that Wor3 is highly integrated into the previously described circuit regulating white-opaque switching and that it controls a subset of the opaque transcriptional program.
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