Such mutant strains are of potential use for investigating ways to improve extracellular ammonium bioproduction.
These parental and mutant strains are now used for large-scale production of a variety of PUFAs.
Statistical analyses of the length and width distributions indicated that the observed differences between the wild-type strain and these two pmp23 mutant strains are significant (Mann-Whitney p-values < 0.0001, see Fig. 2a).
We find that the responses of the magnetic and mutant strains are well described by a relatively simple analytical model, an analysis of which indicates that the key benefit of magnetotaxis is an enhancement of a bacterium's ability to detect oxygen, not an increase in its average speed moving away from high oxygen concentrations.
Such mutant strains are characterized by cross-resistance to fosfomycin, by susceptibility to efflux pump inhibitors, by disability to use glycerol 3-phosphate as a carbon source or by increased activity of the promoter controlling the expression of the glpABC regulon when grown in presence of fosmidomycin.
Importantly, these mutant strains are attenuated in animals.
The WT and mutant strains are visually undistinguishable.
The detailed enzyme activities from the wild-type and mutant strains are given in Table 2.
The reductions in adhesion or invasion that were observed in each of the mutant strains are represented as percentages.
Such risks would benefit from a strategic investigation of competitive dynamics where the fitness of modified or mutant strains are determined against their WT as a baseline.
Here two risks associated with large-scale cultivation of microalgal mutant strains are assessed by undertaking a series of competitive growth and productivity experiments.
