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The plants were mutant specimens of Arabidopsis thaliana with closed, deformed flowers in which some flower parts were fused together.
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The wild-type GISTs of group 3 had similar levels of CD34 as the KIT-mutant specimens of group 3, also 16-fold greater than that in the KIT-mutant GISTs of group 1 (P = 3 × 10−7).
DeadEasy can be used to compare cell counts between large samples of wild-type and mutant specimens, to infer gene function.
A significant proportion (90%, n = 30) of ΔC3GMS mutant specimens analyzed showed abnormal muscle architecture of the ventral longitudinal muscles.
Examination of these sections indicated that the semicircular canal ducts were absent in all six rescued swr mutant specimens (Fig. 1).
In the case of IGF1, these differences reached statistical significance in all comparisons of PDGFRA-mutant specimens (P = 9 × 10−8 to 4 × 10−2).
In addition, five of eight KIT exon 9-mutant specimens segregated in expression group 1, along with the majority of KIT-mutant specimens localized in the small intestine.
Forty-two of the KIT-mutant specimens clustered in two groups, with 24 in group 1 and 18 in group 3.
An additional 10/33 KRAS-mutant specimens were close to the limit of detection using standard melting curve analysis (Table 4 "Lo-Pos").
High expression of NANOG and positive expression of mutant p53 in the pretreatment biopsy specimens of patients with OSCC were associated with poor survival rates and unfavorable clinicopathological features.
These results demonstrate that NANOG, mutant p53, and CD44 could be used as immunohistochemical markers in the pretreatment specimens of OSCC.
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