Sentence examples for mutant showed dramatically from inspiring English sources

Of the double mutants, the bm3-bm4 mutant showed dramatically enhanced disease symptoms, while disease symptoms in the bm2-bm3 double mutant was lower than in the single bm3 mutant, suggesting a negative effect of the bm2 mutation on virulence in this combination.

By contrast, the phosphorylation of Y71 and Y217 contributed significantly to the overall tyrosine phosphorylation of EB1, as both of the phospho-deficient mutants showed dramatically reduced signals in the immunoblot, with antibodies against phosphorylated tyrosine (Fig. S3B).

Overexpression of Drosophila sec8 cDNA in vivo also caused a noticeable but statistically insignificant reduction in microtubule immunoreactivity, and sec8 loss of function mutants showed dramatically increased microtubule immunoreactivity in NMJs.

Not surprisingly, a double mutant rad8∆ rhp26∆ showed dramatically increased sensitivity.

As shown, systemic Drs induction was dependent on Toll signalling: larvae mutant for spz showed dramatically reduced Drs expression.

Mutant A549C which showed dramatically reduced estrone-3-sulfate and estradiol-17β-glucuronide transport had normal transport of valsartan.

Importantly, both apoc2 mutant zebrafish lines showed dramatically decreased apoc2 mRNA expression and developed hypertriglyceridemia, validating the Apoc2 loss-of-function model.

The present study was motivated by recent results showing that rationally designed mutants of αSynuclein showed dramatically reduced propensity to form insoluble aggregates in solution and in C. elegans, and that these variants of αSynuclein demonstrated enhanced neurotoxicity in mammalian cell lines, Drosophila, C. elegans and cultured rat DA neurons [ 22].

The ΔtolC mutant showed a dramatically reduced secretion of AGEs (Figure 3B) indicating the involvement of TolC in this process.

With less penetrance, sec8P1 mutant third instar larvae showed dramatically abnormal neurite growth (e.g. Fig. 3C) that was never observed in control NMJs.

Unexpectedly, the mutant carrying the ssaN deletion showed dramatically increased proliferation in HLA-B27 cells: 1.4-fold at the 8 h and 3.9-fold at the 24 h time points.