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The rescued viral mutant showed dramatic reductions in levels of both viral RNA and viral protein in host cells.
In A. fumigatus, the calcium/calmodulin-dependent kinases and calcineurin catalytic subunit cnaA mutant showed dramatic hyphal defects, including decreased apical extension and polarized growth (Steinbach et al. 2006).
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In addition, three mutants, envZ, ompR, and envZ/ompR double-mutant, showed dramatic reduction in swarm size, but with increased density.
In addition, nbr mutants showed dramatic loss of climbing ability: while wild-type animals show little change in climbing ability even at 30d (>90% of wild-type flies successfully climbed at 30d), nbr null animals showed a dramatic decline already by 20d (∼50% of flies failed to climb) (Fig. 4C).
Mouse alpha neurexin mutants show dramatic defects in calcium-dependent neurotransmitter release [50], [53].
AtTRM10 and AtTRM82 mutants which showed dramatic decrease of mG and mG modified nucleosides respectively, did not show any phenotype under LD conditions.
Genetic mosaics with Tsc1 Rheb double mutant chromosomes also showed dramatic rescue of photoreceptor axon guidance defects (data not shown).
In contrast, the myb28-1 mutant showed a dramatic reduction in long-chained and a decrease in short-chained aliphatic glucosinolates (Table 4).
The ΔfadD2D1 mutant showed more dramatic growth defects on all FAs than the individual single mutants, indicating that both proteins were involved in the metabolism of all chain-length FAs tested.
This mutant showed a dramatic overproliferation of follicle cells, but the invasive behavior was mild (data not shown).
When exposed to increasing doses of cisplatin and MMC, the fan1-d pso2-d double mutant showed a dramatic reduction in viability compared to the corresponding single mutants or the wild-type (wt) control strain (Fig. 1A, left panel).
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CEO of Professional Science Editing for Scientists @ prosciediting.com