Sentence examples for mutant sequences of from inspiring English sources

In this paper, we present an idea to inhibit the evolving receptors by using an ensemble of all possible single- or double-point mutant sequences of the ligand peptide.

We compared λmaxof 12 groups (Fig. 3), statistically significant differences were observed between wildtype and mutant sequences of all groups (P < 0.05, Student'st- test for paired data).

The two mutant sequences of miR-124 were designed by switching bases at positions 5 and 6 (124mut5-6) and at positions 9 and 10 (124mut9-10), respectively.

In their experimental work, Moldoveanu et al. were able to induce proteolysis in several mutant sequences of calpastatin by deleting one or two specific residues (Lys176, Glu177, or both) from a sequence of wild type rat calpastatin (gi 13540322) [49].

In contrast, in cells transfected with plasmids containing mutant sequences of the PDCD4 3′-UTR, luciferactivityvity was minimally decreased in TE13 cells and the reporter activity in Eca109 cells was even increased.

Then, we used a surface plasmon resonance (SPR) biosensor to test 3 mutant sequences of high ZRANK scores along with a high and a low affinity binding sequence as reported in the literature.

The mutant sequence of cloned PCR products was confirmed by DNA sequencing.

The proposed biosensor can distinguish between the normal sequence and the mutant sequence of ApoB-100 gene, promising a possibility to apply the QD-based biosensor for clinical investigations.

The surviving yeast consisted of RTSH yeast (the mutant sequence of CBM: N18R, S23T, S26S, and T27H) and wild-type yeast (CBM was the original) in a ratio of 1 46.

Based on our findings, we prepared the reporter gene assay with wild or mutant sequence of the hypothetical binding site of TNRC6B and miR-18b.

This investigation presents a new in vitro SNP discrimination mechanism, demonstrated by discriminating between the wild-type and mutant sequence of the mitochondrial A8344G MERRF mutation.