Sentence examples for mutant sequences observed from inspiring English sources

In pooled samples, unlike fully mutant sequences observed in the M2 populations, M1 population sequences often revealed two overlapping sequences, suggestive of heteroduplexes (A9/T10 in TGFBR2 and A7/T8 in ACVR2) (Fig. 5B).

However, even under selective pressure from monoclonal antibodies, very few escape mutant sequences were observed for M2e [30] suggesting that this region is biologically constrained.

The two mutations probably occurred on the same allele because only the double-mutant sequence was observed; the wild-type sequence was absent from this tumor (Fig. 1b).

We compared λmaxof 12 groups (Fig. 3), statistically significant differences were observed between wildtype and mutant sequences of all groups (P < 0.05, Student'st- test for paired data).

The mutant sequences were used in the mutant 3′-UTR constructs.

Wild-type and mutant sequences were compared to identify putative resistance mechanisms.

Sequencing of cDNA from cells infected with this last mutant demonstrated that the parental mutant sequence was retained and that genotypic revertants to the wild-type as well as new mutant sequences were generated.

All mutant sequences were verified by DNA sequencing.

Regenerated mutant sequences were used further for mutant modeling.

Mutant sequences were confirmed by PCR assay.

If both wild-type and mutant alleles were observed in the sequence reads, we categorized the pig as monoallelic mutant, although the ratio of wild-type to mutant alleles might not always be 1.