Sentence examples for mutant proteins based from inspiring English sources
Mutant proteins based on Sso7d were expressed at high yields in the Escherichia coli cytoplasm.
This high-throughput construction system can be used to screen mutant proteins based on their catalytic activity.
Such E006AA LV-AR sorted cells expressed ∼3∶1 ratio of wt-AR to mutant AR protein based upon comparison to parental cells expressing only mutant AR protein (Figure 3D).
Some of the function-unknown genes identified are predicted to encode membrane proteins based on their primary structure and/or the phenotypes of their mutants (Table 1).
To test the validity of the helical arrangement as we observed it in the crystals we designed a non-polymerising mutant of crenactin protein based on the longitudinal interface formed when crenactin subunits come together for the protofilament (Fig. 2D).
Mutant proteins were obtained based on the human tyrosinase cDNA expression plasmid, pTriEx-WT obtained previously [24].
The serine/threonine kinase BUB1 (Budding Uninhibited by Benzimidazole 1) was originally identified in yeast as a checkpoint protein, based on its mutant's incapacity of delaying the cell cycle in response to loss of microtubules.
This work describes the formulation design and development of a novel protein based adjuvant, a double mutant of heat labile toxin (dmLT), based on knowledge of the protein's structural integrity and physicochemical degradation pathways.
The site of inhibition is at the C-terminal end of the protein, based on S. cerevisiae mutant strains that are no longer inhibited by leucine [55], [56] and the crystallization of leucine within the M. tuberculosis protein [31].
Pharmacological chaperones work because they stabilize mutant proteins and the method based on thermodynamic analysis is designed to assess this property straightforwardly.
The energy difference between native and the mutant protein was calculated based on Gibbs-free energy value, and the predicted free energy change was denoted by DDG value.
