Sentence examples for mutant prevalence from inspiring English sources

Increase of mutant prevalence and/or of in vitro resistance are thus relevant indicators of emerging therapeutic failures.

In a study in Singapore, the Gly/Arg 145 mutation was present alone or in combination with other mutations in 70% of the isolated HBsAg mutants from neonatal breakthrough infections, for an overall mutant prevalence of 4.6% in this population (37 ).

A similar decrease in mutant type prevalence is noted in other neighboring countries.

The position in red at 7797493 indicates the last single nucleotide variation (SNV) position in the mutants with prevalence of the alternative allele.

According to the allelic frequency shift the recombination hotspot was located in a 260 bp track delimited by position 7797493, corresponding to the last SNV in the mutants with prevalence of the alternative allele, and position 7797753 corresponding to the first SNV with prevalence of the reference allele (Additional file 13: Figure S7).

Comparing data with older studies in Senegal, a sharp decline in the mutant type Pfcrt prevalence is evident: from 65%, 64%, and 59.5% in samples collected from various sites in 2000, 2001, and 2004 to approximately 30% in our study.

A screening program for school-age children in Taiwan found 27/3,849 patient samples with "a" determinant mutants for a prevalence of 0.7% (38 ).

Finally, a combined, high prevalence of quadruple mutant (triple mutant Pfdhfr + 437G mutations) haplotype was noted in both areas in 2009 but as well seemed to decrease in 2010.

For example, the prevalence of mutant alleles of pfcrt 76T decreased from 64.5% in 2002 to 16% in 2004 and that of mutant pfmdr1 86Y alleles decreased from 46.6%to2.7%7% two and half year after CQ withdrawal in coastal Tanzania [ 38].

A quantitative real-time LCR protocol was developed to assess the prevalence of mutant (V136) polymorphism in extracts from DNA pools (genomic or plasmid) and natural extracts from individual ovine milk samples.

This suggests that the high prevalence of mutant genotype may increase the susceptibility to oxidative stress associated diseases.