Sentence examples for mutant predicted to from inspiring English sources

We identify a mutant predicted to lead to increased interfacial hydrophobic contacts (N92F) that shows markedly increased self-association properties on native gradient gels.

Specifically, the T14M/T15K mutant, predicted to impair ATP hydrolysis, as well as the W125D substitution, which deforms and adds charge to the catalytic cleft, exhibited virtually complete abrogation of kinase function.

Generation of triple lysine mutants predicted to completely disrupt the putative TMD allowed us to examine TMD function in the full-length proteins.

In our human DC experiments, mutants predicted to result in a non-mannose capped LAM (Rv2181, Rv1635c, Rv1565c) all had a fitness cost both 3 days and 7 days post-infection (Additional file 4).

Using genetic rescue approaches, CPX mutants predicted to prevent the formation of the zig-zag array (CPX GPGP) disrupt the ability of CPX to clamp spontaneous release, while mutations predicted to enhance the CPXacc t-SNARE interaCPXacc t-SNARElamp mutatinteractiont a strong clamping ability (Cho et al., 2014).

Measured by flow cytometry, the mutants predicted to enforce pairing within each monomer functioned better than those enforcing the interaction between the monomers; although none of the four mutants silenced EGFP as efficiently as the canonical repeat A 2-mer, suggesting that there may be more complex structures involved.

The M4 mutant is predicted to lose the shared GATA1/GATA2 site and the downstream SP1 site, The M6 mutant loses a predicted binding site for zeste homolog/TCERG1.

Synthetic peptides corresponding to mutant proteins predicted to arise from MSI-associated frameshift mutations have been shown to be immunogenic.

Therefore cone photoreceptor degeneration caused by GCAP1-Y99C mutare are predicted to also respond favorably to prolonged light exposure.

All other codons of the gene remain wild-type, therefore the mutant is predicted to be non-polar.

The secondary structure of the 152 167 peptide and S158E mutant is predicted to contain a beta-strand (DNAMan software, Lynnon Biosoft).