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One explanation regarding the lack of efficacy in the KRAS mutant population is that every 2 weeks dosing of ganetespib was not sufficient to suppress the KRAS pathway.
Most, if not all, of the FST information from all insertion mutant population is available in rice browsers RiceGE and OygenesDB.
By taking advantages of its distinctive color of leaves and grains, semi-dwarfism, early flowering and nutrient- rich grains, such mutant population is valuable for discovering mutation expressing useful genetic variation for both agronomic and nutritive characteristics.
The gene-indexed mutant population is a key resource for functional genomics and the International Rice Functional Genomics Consortium IRFGCC) has generated gene-indexed mutants that are available to study the functions of around 30,000 genes.
The total mutant population is composed of a sum of J i.i.d quantities distributed as Q, and J itself is Poisson.
Sorting genes based on differential expression only served to describe differences in the extent to which each mutant population is 'leaky' (i.e., the disrupted loci caused large defects in bradyzoite formation but did not completely abolish this process).
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M82 mutant population was visually phenotyped in the field and categorized into a morphological catalogue that can be searched and accessed via the web (http://zamir.sgn.cornell.edu/mutants/).edu/mutants/
After 18 days under multiple-stress about 70% of the Δ-tgs1 mutant population was found to be acid-fast staining positive, whereas in the wild type Mtb and the C-Δ-tgs1 population only about 30% of the cells were acid-fast positive (Fig. 11B).
In contrast, the high rate of segmental duplications within the mutant population was unexpected.
Raw Illumina reads from each sequenced mutant population were deposited in the Dryad Digital Repository (doi: http://10.5061/dryad.3sk8).
The soybean FN mutant population was developed by exposing >120,000 soybean seeds of cv 'M92-220' to fast neutron radiation doses of 4, 8, 16, or 32 Gy (Bolon et al. 2011).
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